24-Hour Emergency Room in Odessa, TX

Open 24 hours a day, 7 days a week. Board-certified ER physicians are available onsite to provide expert care. We treat a wide range of emergencies, including fractures, chest pain, abdominal pain, migraine treatment, and pediatric emergencies. On-site CT scans, X-rays, labs, and IV medications. We have everything needed to treat you quickly and effectively.
Walk-ins are always welcome. Online appointment is optional. Walk-ins are always welcome. If you are experiencing a life-threatening emergency, call 911.
What our patients say
“The staff is very friendly. I’ll stop by to grab a face mask and was met with pleasure and smiles. Very welcoming I will be back for Care.
“Absolutely amazing staff! In and Out with a smile! If you or anyone has any emergency services, trust me this is the place to come to!
“I had a earwax situation going on and they was able to help me relieve it immediately. the staff was also very friendly
Visit our Odessa ER

“When patients walk into SignatureCare Emergency Center’s emergency room, they are often facing some of the most stressful moments of their lives. Our team is committed to providing prompt medical care, clear communication, and compassionate support every step of the way.”

“Every patient who walks through our doors deserves to feel heard, respected, and cared for. Our team at SignatureCare Emergency Center works around the clock to deliver expert emergency treatment while helping patients and their families find reassurance during difficult times.”

“Emergency care is about more than treating an illness or injury; it is about being there when our patients need help most. SignatureCare Emergency Center’s goal is to provide timely, high-quality medical attention with the compassion and dignity every patient deserves.”
| Our emergency center has received The Joint Commission Gold Seal of Approval®. We are recognized as an Accredited Free-Standing Emergency Center by the Center for Improvement in Healthcare Quality (CIHQ). |
Why Should You Choose SignatureCare Emergency Center?
Your health and comfort are our top priority. As a nationally accredited emergency care provider, we are open around the clock and trusted by thousands of patients for delivering exceptional care. Our dedicated physicians combine clinical expertise with genuine compassion to ensure every patient receives the quality treatment they deserve.

Not sure whether to go to an ER visit or an urgent care center?
Not sure where to go for care? When your condition requires more than an urgent care clinic can handle, SignatureCare Emergency Center in Odessa is here for you. Our ER is equipped with advanced imaging technology for diagnostic testing. Our board-certified emergency physicians provide prompt evaluations.
Still have questions? Don't hesitate to call us anytime at 432-366-0945. Our caring team is always ready to help.
Choose ER care for:
Urgent care may be better for:
Still not sure? Call us now at 432-366-0945, and our team can help guide you.
When you arrive at our ER
From walk-in to discharge — here's what happens. No long wait in a crowded waiting room. Average time from walk in to discharge is under 90 minutes for most patients.
Walk in
A nurse greets you within minutes of your arrival.
Quick triage
Your vitals taken and concerns addressed.
See a doctor
Board-certified ER physician at your bedside. CT, X-ray, or labs start immediately if needed.
Treat & discharge
Clear plan, prescriptions sent to your pharmacy, and a follow-up call the next day.
Inside our Odessa ER
- Multi-slice CT
- Digital X-ray
- Ultrasound
- COLA-certified lab onsite
- Pediatric-friendly rooms
- Welcoming lobby





Insurance and Billing Information
We understand that navigating insurance and billing can be stressful. SignatureCare Emergency Center in Odessa is a licensed freestanding emergency room, and as such, ER billing differs from urgent care billing. We accept most major national insurance plans, including Workers' Compensation, and our knowledgeable team is happy to walk you through your coverage and what to expect when you visit us.
Have questions? Call our Odessa facility anytime at 432-366-0945. We are open 24/7 for your convenience.
For serious or life-threatening emergencies, please call 911 or visit the nearest emergency room immediately.
Frequently Asked Questions
We're open. Walk in anytime.
No appointment needed. Board-certified ER physicians are available 24/7 at our Odessa, TX Emergency Room.

